Vitamin C: Cost, Evidence & ROI

Evidence-based cost-benefit analysis of Vitamin C.

Monthly cost

$16

QALY gain per year

+0.012

Return on investment

+74.0x

Evidence level

Medium (moderate clinical evidence)

What the research shows

Vitamin C supplementation has been shown to improve perioperative outcomes in total hip and knee arthroplasty, potentially reducing complications and enhancing recovery. It also plays a role in preventing preterm birth during pregnancy, suggesting its importance in maternal and fetal health.

Reported benefits

• May enhance recovery and reduce complications in surgical patients, particularly in hip and knee arthroplasties.
• Potentially lowers the risk of preterm birth in pregnant women.
• Supports immune function and may help reduce the duration of common colds.
• Acts as an antioxidant, protecting cells from damage by free radicals.

Who it is for

Individuals undergoing total hip or knee replacement surgery, pregnant women, and those at risk of preterm birth may benefit most from vitamin C supplementation.

Considerations

Vitamin C is generally safe when taken at recommended doses, but high doses can lead to gastrointestinal disturbances and may interact with certain medications, such as anticoagulants. Individuals with conditions like hemochromatosis should avoid excessive vitamin C due to increased iron absorption.

Compare other supplements by cost and evidence

Educational and research purposes only. Always consult a healthcare professional before starting any supplement regimen. ROI is modelled at $100,000 per quality-adjusted life year; see the methodology.