Vitamin B6: Cost, Evidence & ROI

Evidence-based cost-benefit analysis of Vitamin B6.

Monthly cost

$24

QALY gain per year

+0.013

Return on investment

+53.2x

Evidence level

Medium (moderate clinical evidence)

What the research shows

Vitamin B6 has been shown to be effective in reducing mastalgia and may improve treatment responses for patients experiencing acute mania when used in combination with sodium valproate.

Reported benefits

• Reduces mastalgia
• May improve treatment responses for acute manic episodes in bipolar I disorder
• Supports overall brain health
• May help alleviate symptoms of anxiety and depression

Who it is for

Individuals with bipolar I disorder, particularly those experiencing acute manic episodes, and women experiencing mastalgia may benefit from Vitamin B6 supplementation.

Considerations

Vitamin B6 supplementation may interact with certain medications, including blood thinners and certain antidepressants. Individuals with kidney or liver disease should consult their healthcare provider before taking Vitamin B6 supplements. The recommended dietary allowance (RDA) for Vitamin B6 is 1.3-1.5 mg/day for adults.

Compare other supplements by cost and evidence

Educational and research purposes only. Always consult a healthcare professional before starting any supplement regimen. ROI is modelled at $100,000 per quality-adjusted life year; see the methodology.