Vitamin B12: Cost, Evidence & ROI

Evidence-based cost-benefit analysis of Vitamin B12.

Monthly cost

$26

QALY gain per year

+0.013

Return on investment

+49.0x

Evidence level

Medium (moderate clinical evidence)

What the research shows

Vitamin B12 plays a crucial role in neural tube development and folate metabolism. It is essential for DNA synthesis, red blood cell formation, and neurological function.

Reported benefits

• Supports healthy neural tube development in fetuses
• Helps prevent neural tube defects during pregnancy
• Supports red blood cell production and prevents anemia
• Maintains healthy neurological function

Who it is for

Pregnant women or individuals with B12 deficiency are likely to benefit most from Vitamin B12 supplementation.

Considerations

It is important to consult a healthcare provider before starting Vitamin B12 supplementation, especially for individuals with certain medical conditions or taking medications that may interact with B12. Excessive intake of Vitamin B12 can lead to potential side effects and interactions with other medications.

Compare other supplements by cost and evidence

Educational and research purposes only. Always consult a healthcare professional before starting any supplement regimen. ROI is modelled at $100,000 per quality-adjusted life year; see the methodology.