Glucosamine: Cost, Evidence & ROI

Evidence-based cost-benefit analysis of Glucosamine.

Monthly cost
$31
QALY gain per year
+0.007
Return on investment
+21.6x
Evidence level
Medium (moderate clinical evidence)

What the research shows

Glucosamine supplementation has shown evidence of reducing the risk of type 2 diabetes based on Mendelian randomization studies. It may help improve glucose metabolism and insulin sensitivity.

Reported benefits

Who it is for

Individuals at risk of developing type 2 diabetes or those looking to support their metabolic health may benefit most from glucosamine supplementation.

Considerations

While glucosamine is generally considered safe for most people, individuals with shellfish allergies should avoid it. It may interact with certain medications, so consulting a healthcare provider before starting supplementation is recommended. Additionally, the evidence supporting its benefits is still evolving, and more research is needed to fully understand its effects on type 2 diabetes risk.

Compare other supplements by cost and evidence

Educational and research purposes only. Always consult a healthcare professional before starting any supplement regimen. ROI is modelled at $100,000 per quality-adjusted life year; see the methodology.